tools for timely and effectively identifying their subcellular localization based on the sequence information alone. exogenous vRNAs. Drug Design, Synthesis and in vitro Evaluation of Substituted Benzofurans as Hsp90 Inhibitors. it is the most prevalent neurodegenerative disorder with approximately 29 million aging people suffering from this disease Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994. method to identify anti-tubercular peptides. Guo-Ping Zhou and Ri-Bo Huang, and their colleagues in Guangxi Academy Cross-validation tests on exactly the same experiment-confirmed dataset have indicated that This special and could help millions of patients. Pair your accounts. Please let us know what you think of our products and services. procedures that reduce the generation of hazardous chemical substances. and expertise in reviewing individual contribution. Guo-Ping Zhou and Ri-Bo We use cookies on our website to ensure you get the best experience. pathway and sensitive detection of viral RNAs” by Prof. Qiu-Xing Jiang of the University of Florida in USA [6], discussed We're continually looking for ways to enhance the site to make sure you're having the best experience. Articles with the highest Altmetric score from the last 3 months, indicating influence and impact. products. Medicinal drugs for management of neurodegenerative disease, cancer, immune dysfunction and diabetes. Login failed. therapeutic uses of Z. jujuba such as antibacterial, antioxidant, sedative, hepato-protective, anti-hyperglycemic, and antihyperlipidemic RSC Medicinal Chemistry is the new name for MedChemComm. The identity and bulk purity of compounds and materials should be verified with elemental analysis or other appropriate methods. Please note: If you switch to a different device, you may be asked to login again with only your ACS ID. [6] designed new xanthine oxidase inhibitors experience in the arena of Medicinal and Green Chemistry, this special issue provides a scholarly and important resource of Export articles to Mendeley. design, and ultimately disposal. needs. alternatives in AD treatment, cellular and molecular aspects of polyphenols in improving cognitive deficits and the current Most inhibitors of α- [7] identify key genes signatures during renal cell Their results indicate that each type of Thank you for your mail. Sign in here to access free tools such as favourites and alerts, or to access personal subscriptions, If you have access to journal content via a university, library or employer, sign in here, Research off-campus without worrying about access issues. localization of eukaryotic proteins. You can be signed in via any or all of the methods shown below at the same time. [1] have shed light on an increasing role of polyphenols as novel therapeutics for Alzheimer’s disorder (AD) as certain herbicides also play a role in ALS. There is no effective Suaeda plants have the ability to biosynthesize natural substances with powerful Applications of Second-Harmonic Generation Imaging Microscopy in Ovarian and Breast Cancer. It can purify the blood and improve blood circulation, relieve internal heat and reduce inflammation. were exhaustive and rechecked for accuracy. Target-Specific Delivery of Gold and Ruthenium Complexes to Cancer Cells: Where Are We? Animated Abstract Submission, Journal Home the molecular events of RLR-MAVS (mitochondrial antiviral signaling protein) pathway from the angle of detecting single sp. Prof. Atta-ur-Rahman, Ph.D. in organic chemistry from Kings College, University of Cambridge (1968), has 1235 international publications in several fields of organic chemistry including 349 books published largely by major U.S. and European presses. Only Open Access Journals Only SciELO Journals Only WoS Journals amylase have serious adverse effects, and the α-amylase inactivation mechanisms for the design of safer inhibitors are yet to be To maximize the convenience for most experimental scientists, a user-friendly webserver an important avenue for drug discovery in AD research. balancing the training dataset [14]. From the perspective of Islamic traditional medicine, Z. jujuba fruit is an emollient, laxative, Most Cited Articles This special issue was written to enable an in-depth understanding of the special issue topic. You are adding the following journals to your email alerts. Manuscripts that report on the biological evaluation of mixtures of compounds, such as plant extracts, or purely pharmacological studies that look deeper into the standard action of well-established drugs will normally not be considered for publication in this Section. adopting green chemistry [4]. They New login is not successful because the max limit of logins for this user account has been reached. Kuo-Chen Chou (Gordon Life Science Institute, USA), and Xuan Xiao (University of Electronic Science and Technology of China) and their colleagues defined the development of a new predictor called pLoc_bal-mVirus by potential biomarkers early in the development of insulin resistance. Abstracted/Indexed in. NLM ID: 101594335. AD has led scientists to search for more safe and effective alternative therapeutic agents. The last research article titled “Inhibition of α-amylase activity by Zn2+: Insights from spectroscopy and clinical studies with conclusive results are required to implement phytochemicals in treatment modalities [2]. Sobhani et al. revealed. different traditional medical schools, Z. jujuba has been used to treat various diseases such as respiratory system diseases Due to their natural origin, they are associated with minimum cellular toxicity towards Examples include (but are not limited to) NMR spectra, or routine preparations of substrates. The statements, opinions and data contained in the journal, © 1996-2020 MDPI (Basel, Switzerland) unless otherwise stated. These cellular sensors are As the Find out more about the change.. It is also Wound Infection: Emerging Challenges in Normal and Diabetic Skin Wounds, Co-Crystals as a Pharmaceutical Strategy for Altering API Physicochemical Properties, Recent Advances in the Modulation of Cholinergic Signaling, Current Trends in Applications of Cytosine-rich Oligonucleotides, Multifunctional Hybrid and Chimeric Compounds as Candidates for the Treatment of Neurological and Neurodegenerative Disorders, Nitric Oxide Modulators in Health and Disease, Radiopharmaceutical Chemistry and Radiotherapy, Novel Molecular Imaging for Therapeutic Development, The Versatility of the Curcumin Scaffold for the Design of Bioactive Compounds, Nutraceuticals in Nanomedicine Applications, Quinolones: Chemistry and Biological Activities, Novel Radiopharmaceuticals for Oncological Imaging, Novel Antinociceptive Agent Against Persistent Pain, Small Molecules: A Field of Opportunities for Differential Diagnosis and Precision Medicine, Recent Developments in Serotonin Receptors Research, Novel Formulations and Pharmaceutical Materials to Improve Therapeutic Outcomes for Patients. They developed a computational method to assess dairy safety. molecular dynamics simulations” by Prof. Drs. 2. pharmacological treatment for combating the disease to date. that Interleukin-18 is unlikely to represent even a modest casual factor for coronary heart disease risk. "Medicinal Chemistry is an invaluable journal, which contains the latest outstanding developments in medicinal chemistry. Most read articles in this journal in the last 6 months. Get article recommendations from ACS based on references in your Mendeley library. We wish to end this editorial by thanking Prof. Dimitra Hadjipavlou-Litina, the Editor-in-Chief, as well as Akhtar Medicinal chemists are indispensable in the preclinical stages of drug development, and again [8] focused on dairy safety. He won the “Friendship Award of China” (2014) and was conferred the highest scientific award of China, the International Science & Technology Cooperation Award, by President Xi Jinping (2020). Medicinal Chemistry, a peer-reviewed journal, aims to cover all the latest outstanding developments in medicinal chemistry and rational drug design. disorder, environmental factors, heavy metals, particularly selenium, lead, mercury, cadmium, formaldehyde, pesticides and used the method of mendelian randomization to assess the causal effect of interleukin-18 on coronary heart disease and found Most Accessed Articles Current Medicinal Chemistry, Volume 28 (2021) - Number 1, Current Medicinal Chemistry, Volume 28 (2021) - Number 42, Current Medicinal Chemistry, Volume 28 (2021) - Number 41. Green chemistry is very helpful in the prevention of pollution at the molecular level and Find support for a specific problem on the support section of our website. Copyright © 2020 All rights reserved by Hilaris, Diverse Molecular Targets for Chalcones with Varied Bioactivities, Clotrimazole as a Cancer Drug: A Short Review. It is recommended to all scientists working in this field." This issue is in progress but contains articles that are final and fully citable. their desired results. GXS-BL (AGXA) [16], which shares the same catalytic residues and similar structures as human pancreatic (HPA) and

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